Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | VCP | P55072 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | AQP1 | P29972 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900961 | 0.86 | VCP (0.56) | APPNPY5RSLC6A4VCP | |
| SCHEMBL8898282 | 0.82 | NPY5R (0.47) | APPNPY5RSLC6A4VCPMAPT | |
| SCHEMBL8900660 | 0.82 | ADRB2 (0.51) | APPNPY5RSLC6A4MAPTAQP1 | |
| SCHEMBL2636281 | 0.79 | NPY5R (0.64) | APPNPY5RSLC6A4MAPTAQP1 | |
| Hydrochloric Acid SCHEMBL8906965 | 0.78 | NPY5R (0.62) | APPNPY5RSLC6A4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2675360 | 0.78 | NPY5R (0.62) | APPNPY5RSLC6A4NPC1RAB9A | |
| SCHEMBL8901221 | 0.76 | DCPS (0.51) | APPNPY5RSLC6A4VCPMAPT | |
| SCHEMBL8900115 | 0.75 | NPY5R (0.46) | NPY5RSLC6A4VCPMAPTAQP1 | |
| Hydrochloric Acid SCHEMBL8899118 | 0.74 | NPY5R (0.45) | NPY5RSLC6A4VCPMAPTAQP1 | |
| Hydrochloric Acid SCHEMBL8900266 | 0.73 | NPY5R (0.66) | APPNPY5RSLC6A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |