Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900335 | 0.86 | KMT2A (0.35) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL17309878 | 0.83 | PTGS2 (0.47) | ALDH1A1MAPK1KDM4EHPGDHTT | |
| SCHEMBL7758054 | 0.81 | NPC1 (0.42) | GAAMAPK1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8712483 | 0.80 | GAA (0.49) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL8900888 | 0.79 | TNKS2 (0.40) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL8777951 | 0.76 | ALDH1A1 (0.52) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL8900529 | 0.75 | ALDH1A1 (0.41) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL11853280 | 0.73 | HSPA5 (0.39) | GAAALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL1878866 | 0.70 | PTGS2 (0.39) | CYP3A4ALOX15 | |
| SCHEMBL14466905 | 0.70 | PTGS2 (0.36) | MAPK1HPGDHTTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688822-A | ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIALLERGEN | G.D. SEARLE & CO. (US) | 1997-11-18 | — | — | US | disclosed |