Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900888 | 0.88 | TNKS2 (0.40) | ALDH1A1MAPTKDM4EMAPK1GSR | |
| SCHEMBL5609679 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EMAPK1GSR | |
| SCHEMBL8900335 | 0.79 | KMT2A (0.35) | ALDH1A1MAPTKDM4EMAPK1GSR | |
| SCHEMBL11853280 | 0.78 | HSPA5 (0.39) | ALDH1A1MAPTKDM4EMAPK1GSR | |
| SCHEMBL7758054 | 0.78 | NPC1 (0.42) | MAPK1HPGDSMN1; SMN2HTTTSHR | |
| SCHEMBL28177142 | 0.77 | GAA (0.47) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A | |
| SCHEMBL6567279 | 0.76 | DHFR (0.43) | ALDH1A1MAPTKDM4EMAPK1GSR | |
| SCHEMBL17309878 | 0.76 | PTGS2 (0.47) | ALDH1A1KDM4EMAPK1HPGDHTT | |
| SCHEMBL8901066 | 0.75 | GAA (0.34) | ALDH1A1MAPTKDM4EMAPK1HPGD | |
| SCHEMBL3812731 | 0.75 | CYP1A2 (0.55) | ALDH1A1MAPTKDM4EMAPK1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688822-A | ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIALLERGEN | G.D. SEARLE & CO. (US) | 1997-11-18 | — | — | US | disclosed |