Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 8/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047742 | 0.98 | KMT2A (0.43) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL21743123 | 0.92 | KMT2A (0.47) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9045360 | 0.87 | MAPT (0.46) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8822085 | 0.84 | NAAA (0.51) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30426960 | 0.84 | NAAA (0.51) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6684679 | 0.84 | NAAA (0.51) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12687063 | 0.84 | KMT2A (0.42) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15251093 | 0.80 | KMT2A (0.40) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12687057 | 0.78 | TGM2 (0.46) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6713336 | 0.77 | TERT (0.45) | KMT2AMAPTCYP1A2CYP2C19NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675031-A | 4-hydroxy-2-cyclopentenone derivatives and anticancer agent and bone formation accelerator containing the same | TEIJIN LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0448726-B1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0659728-A1 | 4-HYDROXY-2-CYCLOPENTENONE DERIVATIVE AND CARCINOSTATIC AND OSTEOGENESIS PROMOTER CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338844-A | 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient | TEIJIN LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0448726-A1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1991-10-02 | — | — | EP | disclosed |