Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903032 | 0.92 | MAPT (0.36) | ADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL8902599 | 0.90 | TSHR (0.40) | TACR1ALDH1A1HPGDAKR1B1ELANE | |
| SCHEMBL8903038 | 0.89 | CASR (0.39) | CASRADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL8901319 | 0.87 | MAPT (0.41) | CASRP2RX3ADRA1AHRH1ADRA1B | |
| SCHEMBL8902754 | 0.85 | TACR1 (0.39) | TACR1AKR1B1 | |
| SCHEMBL8901027 | 0.83 | CASR (0.41) | CASRTACR1NR1I2 | |
| SCHEMBL8901238 | 0.82 | CASR (0.42) | CASRP2RX3TACR1ALDH1A1KDM4E | |
| SCHEMBL8902054 | 0.82 | ADRA1A (0.38) | ADRA1AHRH1ADRA1BALDH1A1KDM4E | |
| SCHEMBL8902072 | 0.81 | ADRA1A (0.41) | CASRADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL8902466 | 0.81 | CASR (0.42) | CASRTACR1ALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188008-B2 | Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX4, PRDX1 | CASR 3764/4885P2RX3 219/4885ADRA1A 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.