Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902333 | 0.85 | PARP10 (0.50) | MAPTSLC6A4KCNH2HTR2AKMT2A | |
| SCHEMBL9097722 | 0.83 | PNLIP (0.52) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL20944605 | 0.79 | MAPK1 (0.55) | MAPTKMT2AMEN1PARP10ALDH1A1 | |
| SCHEMBL11696831 | 0.79 | KMT2A (0.63) | MAPTSLC6A4KCNH2HTR2AKMT2A | |
| SCHEMBL5364405 | 0.78 | CYP1A2 (0.51) | MAPTKMT2AMEN1POLBPARP10 | |
| SCHEMBL4449413 | 0.78 | PTGER4 (0.57) | SLC6A4KCNH2HTR2ASLC6A3TDP1 | |
| SCHEMBL16319473 | 0.77 | PARP10 (0.49) | MAPTSLC6A4KCNH2HTR2AKMT2A | |
| SCHEMBL9096671 | 0.76 | TDP1 (0.59) | MAPTKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL6760076 | 0.76 | USP2 (0.54) | MAPTKMT2ATDP1PARP10USP2 | |
| SCHEMBL26936666 | 0.76 | KMT2A (0.61) | MAPTKMT2AMEN1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |