Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589289 | 0.90 | GAA (0.51) | USP2ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL9097722 | 0.87 | PNLIP (0.52) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL3223768 | 0.87 | HSD17B10 (0.52) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL10610718 | 0.87 | USP2 (0.67) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL6760192 | 0.85 | USP2 (0.53) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL4242980 | 0.81 | PARP10 (0.63) | MAPTALDH1A1GAAHPGDGLA | |
| SCHEMBL570110 | 0.79 | GAA (0.61) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL11660466 | 0.79 | TTR (0.55) | USP2MAPTALDH1A1GAAHPGD | |
| SCHEMBL8782253 | 0.78 | SLC6A3 (0.61) | MAPTALDH1A1CA1CA2KMT2A | |
| SCHEMBL6757032 | 0.78 | ALDH1A1 (0.55) | MAPTALDH1A1GAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720424-B1 | VEGF (VASCULAR ENDOTHELIAL GROWTH FACTOR) RECEPTOR ANTAGONISTS AND ANGIOGENESIS INHIBITORS SUPPRESS VASCULAR HYPERPERMEABILITY; PHENYLALKYLCARBONYL SUBSTITUENT ON THE AMINO | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1193246-A1 | AMINOBENZOIC ACID DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-04-03 | — | — | EP | disclosed |