Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723285 | 0.76 | APP (0.43) | GBA1EGFRPDGFRBKDRKDM4E | |
| SCHEMBL4031318 | 0.72 | KDM4E (0.49) | GBA1EGFRPDGFRBKDRKDM4E | |
| SCHEMBL23723247 | 0.72 | APP (0.42) | GBA1EGFRPDGFRBKDRKDM4E | |
| SCHEMBL3113281 | 0.69 | ADORA2A (0.42) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL3113231 | 0.69 | APP (0.41) | EGFRPDGFRBKDRAPPMEN1 | |
| SCHEMBL3113186 | 0.69 | EGFR (0.49) | EGFRPDGFRBKDRAPPNCF1 | |
| SCHEMBL1685039 | 0.69 | EGFR (0.52) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL3113119 | 0.68 | MAOA (0.42) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL1259372 | 0.68 | GABBR2 (0.50) | ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL1685079 | 0.68 | EGFR (0.51) | EGFRPDGFRBKDRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |