Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892597 | 0.77 | KDM4E (0.43) | KDM4ESMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL8890391 | 0.72 | HDAC6 (0.58) | KDM4ESMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL8487616 | 0.70 | KDM4E (0.59) | KDM4ESMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL8432918 | 0.69 | CBX7 (0.47) | KDM4ESMN1; SMN2KMT2AMEN1EGFR | |
| SCHEMBL4849852 | 0.69 | GRIA1 (0.52) | KMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL8901336 | 0.68 | GRIA1 (0.35) | KMT2A | |
| SCHEMBL12560654 | 0.68 | HCAR2 (0.44) | KDM4EKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL5712332 | 0.68 | KDM4E (0.51) | KDM4ESMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL14123262 | 0.67 | KDM4E (0.49) | KDM4ESMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL7231747 | 0.67 | KDM4E (0.67) | KDM4ESMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |