Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.42 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.42 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487991 | 0.88 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL8890391 | 0.85 | HDAC6 (0.58) | KDM4ESMN1; SMN2CBX7CDYL2CDYL | |
| SCHEMBL8893031 | 0.84 | GRIN2D (0.48) | CBX7CDYL2CDYLCDY1; CDY1BHDAC1 | |
| SCHEMBL8432918 | 0.80 | CBX7 (0.47) | KDM4ESMN1; SMN2CBX7CDYL2CDYL | |
| SCHEMBL8901340 | 0.77 | KDM4E (0.40) | KDM4ESMN1; SMN2HDAC1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL8890311 | 0.75 | ITGB1 (0.37) | KDM4EHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8487616 | 0.73 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL10488076 | 0.72 | HDAC1 (0.53) | KDM4EHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL7231747 | 0.70 | KDM4E (0.67) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8907357 | 0.68 | CA12 (0.38) | MEN1CYP2C9CYP2C19KMT2AGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |