Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899571 | 0.93 | HMGCR (0.34) | HMGCRGCGR | |
| SCHEMBL8899623 | 0.93 | HMGCR (0.34) | HMGCRGCGR | |
| SCHEMBL8879008 | 0.92 | HMGCR (0.36) | HMGCRGCGR | |
| SCHEMBL8876699 | 0.90 | GCGR (0.37) | HMGCRGCGR | |
| SCHEMBL8877778 | 0.87 | HMGCR (0.38) | HMGCRGCGR | |
| SCHEMBL8876731 | 0.85 | HMGCR (0.34) | HMGCRGCGR | |
| SCHEMBL8876603 | 0.85 | HMGCR (0.34) | HMGCRGCGR | |
| SCHEMBL8875951 | 0.83 | HMGCR (0.53) | HMGCR | |
| SCHEMBL8877422 | 0.83 | — | — | |
| SCHEMBL8876900 | 0.82 | GCGR (0.38) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |