SCHEMBL8901360

SCHEMBL8901360

CCc1ccc2sc(SN)nc2c1CC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28140364 0.98
SCHEMBL28016338 0.87 PTGS2 (0.35)
SCHEMBL1771542 0.87 FBP1 (0.37)
SCHEMBL27575961 0.81 MEN1 (0.33) NPC1RAB9A
SCHEMBL10475866 0.80 PTGS2 (0.35)
SCHEMBL28299064 0.79 MEN1 (0.47) RAB9ASMN1; SMN2
SCHEMBL19792554 0.79 ALDH1A1 (0.46) NPC1RAB9ASMN1; SMN2
SCHEMBL1771627 0.76 MEN1 (0.31)
SCHEMBL27839569 0.74 TYR (0.33) NPC1
SCHEMBL2064420 0.74 PPARA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178852-A Rubber composition and vulcanization rubber and its preparation method and application 中国石油化工股份有限公司 2018-06-19 CN claimed
CN-108129719-A Rubber composition for tire tread and preparation method thereof 三角轮胎股份有限公司 2018-06-08 CN claimed
CN-106198828-B The identification method of sulfenamide type accelerators in rubber 北京彤程创展科技有限公司 2018-06-01 CN claimed
CN-106700147-A Rubber composition with low rolling resistance and vulcanized rubber and preparation method and application thereof 中国石油化工股份有限公司 2017-05-24 CN claimed
CN-106987040-B A kind of rubber composition, rubber product, hydralic hose and preparation method thereof 陕西迈纬尔胶管有限公司 2019-06-18 CN disclosed
CN-108633280-A The crosslinked foams manufactured by ethylene/alpha-olefin interpolymers 陶氏环球技术有限责任公司 2018-10-09 CN disclosed
CN-108178852-A Rubber composition and vulcanization rubber and its preparation method and application 中国石油化工股份有限公司 2018-06-19 CN disclosed
CN-106198828-B The identification method of sulfenamide type accelerators in rubber 北京彤程创展科技有限公司 2018-06-01 CN disclosed
CN-107428211-A Tire 株式会社普利司通 2017-12-01 CN disclosed
CN-107406632-A Rubber composition and tire 株式会社普利司通 2017-11-28 CN disclosed
CN-106700147-A Rubber composition with low rolling resistance and vulcanized rubber and preparation method and application thereof 中国石油化工股份有限公司 2017-05-24 CN disclosed
CN-103857736-B There is the tyre surface of Ultra-High Efficiency vulcanization system COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-09-23 CN disclosed
CN-104220506-A Tire thread for improved wear properties MICHELIN RECH TECH 2014-12-17 CN disclosed
CN-103857736-A Tread with ultra efficient vulcanization system MICHELIN RECH TECH 2014-06-11 CN disclosed
CN-101230156-B Magnetic rubber having high magnetic flux density and preparation method thereof ZHONGLIAN YANG 2012-03-21 CN disclosed
CN-101230156-A Magnetic rubber having high magnetic flux density and preparation method thereof ZHONGLIAN YANG (CN) 2008-07-30 CN disclosed
EP-0778852-A1 THERMOSET ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1997-06-18 EP disclosed
WO-1996007681-A1 THERMOSET ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1996-03-14 WO disclosed
CN-1013118-B HIGH-ELASTIC RUBBER PRODUCTS GUTTA PERCHA CHEMICAL INST CHINESE ACADEMY (CN) 1991-07-10 CN disclosed