Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901428 | 0.80 | ESR1 (0.50) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL20410523 | 0.79 | KDM4E (0.50) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL8488526 | 0.78 | KDM4E (0.51) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL8911222 | 0.77 | KDM4E (0.43) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL20409590 | 0.76 | KDM4E (0.53) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL471858 | 0.76 | KDM4E (0.60) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL8900361 | 0.73 | HRH3 (0.43) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL4027768 | 0.73 | LMNA (0.48) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL4794728 | 0.73 | KDM4E (0.50) | KDM4EHTTLMNAMAPTHRH3 | |
| SCHEMBL20409698 | 0.73 | KDM4E (0.42) | KDM4EHTTLMNAMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |
| US-5602104-A | SKIN DISORDERS, CONJUNCTIVE TISSUE DISORDERS, ANTITUMOR AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-02-11 | — | — | US | disclosed |
| US-5434180-A | Skin disorders; retinoid activity; rheumatoid psoriasis; | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-07-18 | — | — | US | disclosed |
| US-5124473-A | Skin disorders; antiinflammatory agents, antiallergens | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-06-23 | — | — | US | disclosed |