Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832615 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL27450990 | 0.75 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27466683 | 0.70 | GAA (0.35) | MAPTALDH1A1KMT2A | |
| SCHEMBL20300394 | 0.70 | ALDH1A1 (0.48) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL8901380 | 0.70 | MAPT (0.59) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL561797 | 0.68 | TP53 (0.67) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL28379145 | 0.67 | PDK1 (0.47) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27780243 | 0.67 | HRH3 (0.31) | — | |
| SCHEMBL21375730 | 0.67 | ALDH1A1 (0.58) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL1712953 | 0.67 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693807-A | Substituted hydroquinone derivatives | CIBA-GEIGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5290939-A | Process for the manufacture of brofaromine and analogs thereof | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |