Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177618 | 0.86 | CTSS (0.46) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL8901402 | 0.82 | CTSK (0.50) | CTSSCTSKGABRB1GABRB2PPARA | |
| SCHEMBL30370648 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL8511514 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL16334202 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL23886587 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL29571369 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL30370355 | 0.81 | CTSS (0.49) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL8900372 | 0.81 | CTSS (0.42) | CTSSCTSKPTPN1GABRB1GABRB2 | |
| SCHEMBL18683503 | 0.80 | CTSS (0.42) | CTSSCTSKPTPN1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686622-A | Thiazolidine derivatives, their preparation and the medicaments containing the same | RHONE-POULENC RORER S.A. (FR) | 1997-11-11 | — | — | US | disclosed |