Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900951 | 0.95 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL8900846 | 0.89 | EDNRA (0.81) | EDNRBEDNRA | |
| SCHEMBL8902335 | 0.84 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL6314775 | 0.81 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8029697 | 0.81 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL8798982 | 0.80 | EDNRB (0.78) | EDNRBEDNRA | |
| SCHEMBL6859336 | 0.79 | PPARG (0.54) | EDNRBEDNRA | |
| SCHEMBL8902400 | 0.78 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL8900567 | 0.77 | EDNRA (0.57) | EDNRBEDNRA | |
| SCHEMBL6857727 | 0.76 | PPARG (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686481-A | INDOLE DERIVATIVES; TREATING HYPERTENSION, RENAL FAILURE, CEREBROVASCULAR DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1994014434-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |