Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.77 |
| ▸ | GALR3 | O60755 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 3/20 | 0.54 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901857 | 1.00 | MAPT (0.77) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL8350586 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL5700581 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL25608056 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL13649348 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL5700584 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL8350588 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL13905975 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL22607967 | 0.87 | MAPT (1.00) | MAPTUCHL3GALR3KMT2ATRPA1 | |
| SCHEMBL19732190 | 0.85 | TRPA1 (0.64) | MAPTUCHL3GALR3KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599837-A | 15-DEOXYPROSTAGLANDINS | SHIONOGI & CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0471856-B1 | 15-DEOXYPROSTAGLANDIN DERIVATIVE | SHIONOGI & CO (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5292754-A | Using 15-deoxyprostaglandin derivative | SHIONOGI & CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |