Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948519 | 0.90 | TRPA1 (0.61) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL2948516 | 0.90 | TRPA1 (0.61) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL30209147 | 0.87 | TRPA1 (0.59) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL21631706 | 0.87 | TRPA1 (0.59) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL8901857 | 0.85 | MAPT (0.77) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL8901863 | 0.85 | MAPT (0.77) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL8903380 | 0.84 | TRPA1 (0.77) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL11614322 | 0.84 | TRPA1 (0.77) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL8903382 | 0.84 | TRPA1 (0.77) | TRPA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL20795023 | 0.83 | CNR1 (0.61) | MEN1ALDH1A1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218815-A1 | MOTOR-ASSOCIATED NEURODEGENERATIVE DISEASE AND METHODS OF TREATMENT | Verge Analytics, Inc. (US) | 2017-12-21 | — | — | WO | disclosed |