SCHEMBL8901914

SCHEMBL8901914

COc1cccc(Oc2ccc(C(=O)c3ccc(C)cc3)cc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.60
MTNR1B P49286 5/20 0.56
MTNR1A P48039 3/20 0.56
PGR P06401 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
STS P08842 1/20 0.52
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
SRD5A2 P31213 1/20 0.51
MAPT P10636 1/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 2/20 0.51
KDM4E B2RXH2 1/20 0.51
TP53 P04637 1/20 0.51
TSHR P16473 1/20 0.51
NFKB1 P19838 1/20 0.51
RAB9A P51151 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026418 1.00 MMP13 (0.60) MMP13MTNR1BMTNR1APGRSMN1; SMN2
SCHEMBL13374185 1.00 MMP13 (0.60) MMP13MTNR1BMTNR1APGRSMN1; SMN2
SCHEMBL14030885 0.97 MMP13 (0.56) MMP13MTNR1BMTNR1APGRSMN1; SMN2
SCHEMBL13026427 0.96 MMP13 (0.56) MMP13MTNR1BMTNR1APGRSMN1; SMN2
SCHEMBL16378706 0.94 MTNR1B (0.62) MTNR1BMTNR1APGRSMN1; SMN2STS
SCHEMBL15760407 0.94 SRD5A2 (0.58) MMP13HSD17B1HSD17B2SRD5A2HTT
SCHEMBL12299803 0.91 STS (0.60) MMP13MTNR1BSMN1; SMN2STSHSD17B1
SCHEMBL6368727 0.91 MMP13 (0.52) MMP13MTNR1BMTNR1APGRSMN1; SMN2
SCHEMBL9914252 0.89 KDM4E (0.56) MMP13SMN1; SMN2MAPTHTTNPSR1
SCHEMBL17206859 0.89 LMNA (0.55) MMP13SMN1; SMN2SRD5A2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773218-B2 Method of making a PEEK-PEmEK copolymer and copolymer obtained from the method SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-03 US disclosed
US-11773218-B2 Method of making a PEEK-PEmEK copolymer and copolymer obtained from the method SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-03 US disclosed
US-20230257505-A1 COPOLYMERS, THEIR PREPARATION AND USE VICTREX MANUFACTURING LIMITED (GB) 2023-08-17 US disclosed
US-20230257505-A1 COPOLYMERS, THEIR PREPARATION AND USE VICTREX MANUFACTURING LIMITED (GB) 2023-08-17 US disclosed
EP-3728400-B1 A METHOD OF MAKING A SHAPED ARTICLE COMPRISING PRINTING LAYERS OF A POLYMER COMPOSITION COMPRISING AT LEAST ONE PEEK-PEMEK COPOLYMER SOLVAY SPECIALTY POLYMERS USA (US) 2023-08-16 EP disclosed
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
US-8187767-B2 Polymeric materials VICTREX MANUFACTURING LIMITED (GB) 2012-05-29 US disclosed
US-7645534-B2 Membrane electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2010-01-12 US disclosed
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP JSR CORPORATION (JP) 2009-06-11 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
US-20070269700-A1 Polymeric Materials CHARNOCK PETER 2007-11-22 US disclosed
US-20070248865-A1 Membrane electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP AFF2, FGFR1, FUS MMP13 4234/4885MTNR1B 4134/4885MTNR1A 3711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.