SCHEMBL8901925

SCHEMBL8901925

COc1cccc(Cc2[c]noc2)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
CHRM3 P20309 1/20 0.45
HTR1B P28222 1/20 0.45
TAAR1 Q96RJ0 3/20 0.44
IDO1 P14902 2/20 0.44
AGXT P21549 2/20 0.44
SIGMAR1 Q99720 1/20 0.43
DHFR P00374 1/20 0.43
HRH3 Q9Y5N1 1/20 0.41
CMA1 P23946 1/20 0.41
LTA4H P09960 2/20 0.40
CNR1 P21554 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
FGFR1 P11362 1/20 0.40
FGFR4 P22455 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828221 0.76 CALM1 (0.42) TAAR1HRH3GPR55
SCHEMBL2099512 0.75 CHRM2 (0.66) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL6978758 0.71 CHRM2 (0.49) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL16060614 0.71 DYRK1A (0.47)
SCHEMBL499957 0.71 AOC3 (0.47) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL22371499 0.71 TAAR1 (0.46) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL27588644 0.71 CHRM2 (0.49) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL2092574 0.70 LTA4H (0.67) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL31739258 0.70 LTA4H (0.67) CHRM2CHRM1CHRM3HTR1BTAAR1
SCHEMBL920277 0.70 CHRM2 (0.47) CHRM2CHRM1CHRM3HTR1BTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5594020-A FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed