SCHEMBL920277

SCHEMBL920277

COc1cccc(Cc2cc[c]o2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
TAAR1 Q96RJ0 3/20 0.46
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
IDH1 O75874 1/20 0.44
HTR1B P28222 1/20 0.43
CMA1 P23946 1/20 0.43
CNR2 P34972 1/20 0.42
CNR1 P21554 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
AOC3 Q16853 1/20 0.42
MAOB P27338 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920282 0.80 LTA4H (0.48) TAAR1IDO1AGXT
SCHEMBL919736 0.80 TAAR1 (0.43) TAAR1IDO1MAOBACHE
SCHEMBL2099512 0.77 CHRM2 (0.66) CHRM2CHRM1CHRM3TAAR1IDO1
SCHEMBL920155 0.77 PNMT (0.46) CHRM2TAAR1IDO1AGXT
SCHEMBL500864 0.76 DHFR (0.49) CHRM2CHRM1CHRM3TAAR1IDO1
SCHEMBL920263 0.76 TAAR1 (0.42) TAAR1IDO1AGXTIDH1
SCHEMBL920538 0.74 CALM1 (0.46) IDO1IDH1GPR55
SCHEMBL6978760 0.73 CHRM2 (0.53) CHRM2CHRM1CHRM3TAAR1IDO1
SCHEMBL4498868 0.73 CHRM2 (0.53) CHRM2CHRM1CHRM3TAAR1IDO1
SCHEMBL18355946 0.73 MAOB (0.67) CHRM2CHRM1CHRM3TAAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
WO-2008126684-A2 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX CHRM2 3049/4885CHRM1 2974/4885CHRM3 4294/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CHRM2 3483/4885CHRM1 2353/4885CHRM3 3486/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 CHRM2 932/4885CHRM1 460/4885CHRM3 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.