Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382174 | 0.88 | GAA (0.50) | HTTGAAKDM4EKMT2APOLB | |
| SCHEMBL8902211 | 0.84 | KDM4E (0.53) | GAAKDM4EPOLBMGAMSI | |
| SCHEMBL7466908 | 0.79 | KDM4E (0.68) | HTTGAAKDM4EKMT2APOLB | |
| SCHEMBL6582728 | 0.79 | KDM4E (0.67) | HTTGAAKDM4EKMT2APOLB | |
| SCHEMBL1018545 | 0.78 | HTT (0.48) | HTTGAAKDM4EKMT2APOLB | |
| SCHEMBL23202774 | 0.77 | GAA (0.64) | GAAKMT2APOLBMGAMSI | |
| SCHEMBL30350284 | 0.77 | GAA (0.64) | GAAKMT2APOLBMGAMSI | |
| SCHEMBL18318870 | 0.77 | GAA (0.58) | HTTGAAKDM4EKMT2APOLB | |
| SCHEMBL987413 | 0.75 | MAPT (0.57) | GAAKDM4EKMT2AATMNPSR1 | |
| SCHEMBL17176838 | 0.75 | KDM4E (0.45) | HTTGAAKDM4EPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |