Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901644 | 0.81 | CTDSP1 (0.44) | KDM4EKMT2AALDH1A1TSHRPOLB | |
| SCHEMBL27341138 | 0.77 | KMT2A (0.34) | KMT2AALDH1A1TSHRPOLBLMNA | |
| SCHEMBL8902153 | 0.67 | HPGD (0.39) | KMT2AALDH1A1TSHRPOLBLMNA | |
| SCHEMBL8527142 | 0.67 | MIF (0.46) | ALDH1A1HTTTDP1 | |
| SCHEMBL21847501 | 0.66 | ALDH1A1 (0.41) | KDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL8527222 | 0.66 | ADRA1A (0.39) | KDM4EKMT2AALDH1A1LMNA | |
| SCHEMBL3354382 | 0.65 | POLB (0.40) | KDM4EKMT2AALDH1A1TSHRPOLB | |
| SCHEMBL10620628 | 0.65 | TSHR (0.42) | KDM4EKMT2AALDH1A1TSHRPOLB | |
| SCHEMBL8529815 | 0.64 | ADRA1A (0.46) | KDM4EALDH1A1 | |
| SCHEMBL8527137 | 0.63 | MIF (0.45) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| CN-1058781-A | New heterocyclic anthracycline hydrocarbon homologue | IAF BIOCHEM INT (CA) | 1992-02-19 | — | — | CN | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |