Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 10/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092563 | 0.74 | MAPK1 (0.41) | ABCC9 | |
| SCHEMBL9371070 | 0.74 | MAPK1 (0.41) | ABCC9 | |
| SCHEMBL9092568 | 0.74 | MAPK1 (0.41) | ABCC9 | |
| SCHEMBL9197856 | 0.73 | HTR1A (0.39) | KCNE1KCNQ1KDM4EHTR1AHTR2B | |
| SCHEMBL9197846 | 0.73 | HTR1A (0.39) | KCNE1KCNQ1KDM4EHTR1AHTR2B | |
| SCHEMBL9530280 | 0.72 | KCNE1 (0.53) | KCNE1KCNQ1KDM4EL3MBTL1ABCC9 | |
| SCHEMBL9198459 | 0.72 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCC9 | |
| SCHEMBL9032544 | 0.72 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8946770 | 0.72 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCC9 | |
| SCHEMBL9198446 | 0.72 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612323-A | ANTIISCHEMIC | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-18 | — | — | US | disclosed |