Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425023 | 0.69 | MAPT (0.68) | MAPTTDP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL30466426 | 0.69 | MAPT (0.68) | MAPTTDP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL12553219 | 0.67 | MEN1 (0.38) | MAPTTDP1DRD2SMN1; SMN2LMNA | |
| SCHEMBL566279 | 0.66 | KMT2A (0.46) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL732725 | 0.66 | MAPT (0.61) | MAPTTDP1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL2589446 | 0.65 | TDP1 (0.43) | MAPTTDP1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31019409 | 0.65 | PTGER1 (0.42) | TDP1MAPK1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9070650 | 0.65 | PTGER1 (0.42) | TDP1MAPK1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8748732 | 0.64 | KMT2A (0.52) | MAPTTDP1KMT2A | |
| SCHEMBL7598320 | 0.63 | MAPK1 (0.49) | MAPTTDP1MAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607625-A | TEST KITS CONTAINING THE DIOXETANES | ABBOTT LABORATORIES (US) | 1997-03-04 | — | — | US | disclosed |