Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.59 |
| ▸ | TXNRD3 | Q86VQ6 | 6/20 | 0.59 |
| ▸ | TXNRD2 | Q9NNW7 | 6/20 | 0.59 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911677 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL6266510 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL28471882 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL1193222 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL18736267 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL16016300 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL6450045 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL4911680 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL4911675 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TXNRD1 | |
| SCHEMBL4070795 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094699-A1 | INHIBITORS OF ABNORMAL PHOSPHORYLATION AND TAU PROTEIN AGGREGATION | UNIVERSITE DE PICARDIE JULES VERNE (FR) | 2023-06-01 | — | — | WO | disclosed |
| US-20180105547-A1 | METHODS FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-04-19 | — | — | US | disclosed |
| US-20170274377-A1 | MICRO NANOPOROUS MEMBRANE, PREPARING METHOD THEREOF AND MICROFLUIDIC DEVICE USING THEREOF | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) | 2017-09-28 | — | — | US | disclosed |
| US-20120301535-A1 | COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME | AQUESTIVE THERAPEUTICS, INC. | 2012-11-29 | — | — | US | disclosed |
| US-20120009260-A1 | NANOPARTICLE FILM DELIVERY SYSTEMS | AQUESTIVE THERAPEUTICS, INC. | 2012-01-12 | — | — | US | disclosed |
| US-7834159-B2 | Pharmacokinetics; glycosyltransferases; vaccines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-16 | — | — | US | disclosed |
| US-7772380-B2 | Ceramide derivatives as modulators of immunity and autoimmunity | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-08-10 | — | — | US | disclosed |
| WO-2010081026-A1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20070238673-A1 | Ceramide derivatives as modulators of immunity and autoimmunity | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2007-10-11 | — | — | US | disclosed |
| US-20070172915-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-26 | — | — | US | disclosed |
| US-7217809-B2 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-05-15 | — | — | US | disclosed |
| US-7183082-B2 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105547-A1 | METHODS FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES | ICOS, HRH2, HRH4 | ALDH1A1 915/4885TSHR 1570/4885LMNA 4647/4885 |
| US-20070238673-A1 | Ceramide derivatives as modulators of immunity and autoimmunity | CERS2, UGCG, SGMS1 | ALDH1A1 4340/4885TSHR 2845/4885LMNA 2169/4885 |
| US-20120009260-A1 | NANOPARTICLE FILM DELIVERY SYSTEMS | CD63, DSTN, EPCAM | ALDH1A1 994/4885TSHR 2655/4885LMNA 1110/4885 |
| US-20120301535-A1 | COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME | CALCA, LNPEP, IAPP | ALDH1A1 4292/4885TSHR 757/4885LMNA 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.