Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.62 |
| ▸ | HTR1B | P28222 | 8/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686768 | 0.97 | HTR1D (0.64) | HTR1DHTR1BSLC6A4LTA4HHTR6 | |
| SCHEMBL8686765 | 0.77 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8903385 | 0.76 | HTR1D (0.98) | HTR1DHTR1B | |
| SCHEMBL8901244 | 0.76 | HTR1D (0.76) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL8686120 | 0.76 | HTR1D (1.00) | HTR1DHTR1BHTR6HTR1AHTR7 | |
| SCHEMBL8894945 | 0.76 | SLC6A4 (0.60) | HTR1DHTR1BSLC6A4HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL7317904 | 0.75 | HTR1D (0.97) | HTR1DHTR1BHTR6HTR1AHTR7 | |
| SCHEMBL8902545 | 0.75 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL8893980 | 0.75 | HTR1D (0.73) | HTR1DHTR1BSLC6A4 | |
| SCHEMBL8901901 | 0.74 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |