Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760833 | 0.78 | CDK1 (0.46) | CDK1CA2CA1CA9CA5A | |
| SCHEMBL8903404 | 0.77 | ING2 (0.35) | — | |
| SCHEMBL8904163 | 0.76 | PRMT1 (0.35) | CA2KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2881079 | 0.76 | MAPT (0.41) | CA2CA1KMT2ACA7ALDH1A1 | |
| SCHEMBL2880285 | 0.73 | BRD4 (0.38) | KMT2AALDH1A1MAPTGAA | |
| SCHEMBL3283445 | 0.72 | CDK1 (0.42) | CDK1CA2CA1CA9CA5A | |
| SCHEMBL8904001 | 0.72 | ALDH1A1 (0.42) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL2885617 | 0.70 | LMNA (0.33) | HPGDHSD17B10 | |
| SCHEMBL2884897 | 0.69 | L3MBTL1 (0.33) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8904514 | 0.69 | TTR (0.35) | HSD17B10ALDH1A1TDP1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688873-A | POLYISOBENZOTHIOPHENE, POLYISOBENZOFURAN, POLYISOINDOLE AND RELATED POLYMERS, AROMATIC RESINS, SULFONATE GROUP, WATER SOLUBILITY | SHOWA DENKO K.K. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5648453-A | Electroconductive polymer and process for producing the polymer | SHOWA DENKO K.K. (JP) | 1997-07-15 | — | — | US | disclosed |