Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718269 | 0.82 | KMT2A (0.44) | EPHX2MAPTGAATP53ALDH2 | |
| SCHEMBL8903999 | 0.81 | MAPT (0.46) | EPHX2MAPTTP53SMN1; SMN2JAK2 | |
| SCHEMBL8904054 | 0.79 | TPSAB1 (0.49) | EPHX2MAPTTP53SMN1; SMN2POLB | |
| SCHEMBL8718449 | 0.79 | KDM4E (0.43) | EPHX2MAPTGAATP53ALDH2 | |
| SCHEMBL8905612 | 0.69 | PSEN1 (0.39) | MAPTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL22192691 | 0.68 | NPC1 (0.65) | EPHX2MAPTGAATP53SMN1; SMN2 | |
| SCHEMBL8904711 | 0.67 | MAPT (0.43) | MAPTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8903964 | 0.67 | ITGB3 (0.44) | MAPTTP53SMN1; SMN2JAK2ALDH1A1 | |
| SCHEMBL829971 | 0.66 | KMT2A (0.71) | EPHX2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8718013 | 0.65 | SMN1; SMN2 (0.37) | MAPTGAASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |