Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 7/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904212 | 0.89 | ERN1 (0.36) | MEN1NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL8905228 | 0.86 | ERN1 (0.39) | MEN1NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL8904880 | 0.85 | ERN1 (0.37) | ERN1CETPNQO1CDK1 | |
| SCHEMBL8904864 | 0.85 | ERN1 (0.43) | ERN1CETPHSD17B1HSD17B2 | |
| SCHEMBL8904950 | 0.84 | ERN1 (0.38) | MEN1NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL8733903 | 0.82 | PTGDR2 (0.40) | ALDH1A1KMT2ATDP1CETP | |
| SCHEMBL8905400 | 0.80 | NQO1 (0.37) | MEN1ALDH1A1KMT2ATDP1ERN1 | |
| SCHEMBL8906218 | 0.78 | CETP (0.44) | LMNAERN1CETP | |
| SCHEMBL8734287 | 0.77 | KMT2A (0.42) | ALDH1A1KMT2ATDP1ERN1 | |
| SCHEMBL8732768 | 0.75 | AR (0.40) | NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | claimed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |