Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734319 | 0.88 | CTSD (0.40) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8736524 | 0.88 | PTGDR2 (0.45) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8734287 | 0.86 | KMT2A (0.42) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8736063 | 0.85 | CETP (0.49) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8736522 | 0.83 | THRA (0.40) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8734491 | 0.83 | CETP (0.39) | PTGDR2PTPN1TDP1KDM4EALDH1A1 | |
| SCHEMBL8904217 | 0.82 | MEN1 (0.36) | TDP1ALDH1A1KMT2ACETP | |
| SCHEMBL8904212 | 0.81 | ERN1 (0.36) | TDP1ALDH1A1THRATHRBKMT2A | |
| SCHEMBL8905228 | 0.78 | ERN1 (0.39) | TDP1KDM4EALDH1A1HPGDTHRA | |
| SCHEMBL8733885 | 0.77 | KMT2A (0.39) | PTPN1KDM4ETHRATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | claimed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | claimed |
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |