Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.39 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904950 | 0.90 | ERN1 (0.38) | ERN1NQO1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8904217 | 0.86 | MEN1 (0.36) | ERN1NQO1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8904212 | 0.85 | ERN1 (0.36) | ERN1NQO1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8734287 | 0.83 | KMT2A (0.42) | ERN1ALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL8732768 | 0.79 | AR (0.40) | NQO1 | |
| SCHEMBL8733903 | 0.78 | PTGDR2 (0.40) | ALDH1A1KMT2ATDP1KDM4EHPGD | |
| SCHEMBL8904864 | 0.77 | ERN1 (0.43) | ERN1 | |
| SCHEMBL8905400 | 0.76 | NQO1 (0.37) | ERN1NQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL8905392 | 0.75 | NQO1 (0.36) | ERN1NQO1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8904879 | 0.75 | AR (0.37) | ERN1NQO1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | claimed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |