Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 4/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733903 | 0.86 | PTGDR2 (0.40) | KMT2AKDM4ETHRATHRBPTGDR2 | |
| SCHEMBL8733885 | 0.83 | KMT2A (0.39) | KMT2AKDM4EPKMHTTTHRA | |
| SCHEMBL8905228 | 0.83 | ERN1 (0.39) | KMT2AKDM4ETHRATHRBERN1 | |
| SCHEMBL8904950 | 0.81 | ERN1 (0.38) | KMT2AERN1ALDH1A1TDP1 | |
| SCHEMBL8734319 | 0.80 | CTSD (0.40) | KMT2AKDM4ETHRATHRBPTGDR2 | |
| SCHEMBL8736522 | 0.78 | THRA (0.40) | KMT2AKDM4EPKMHTTTHRA | |
| SCHEMBL8904217 | 0.77 | MEN1 (0.36) | KMT2AERN1ALDH1A1TDP1 | |
| SCHEMBL8734491 | 0.77 | CETP (0.39) | KMT2AKDM4ETHRATHRBPTGDR2 | |
| SCHEMBL8904212 | 0.76 | ERN1 (0.36) | KMT2AHTTTHRATHRBERN1 | |
| SCHEMBL8736524 | 0.74 | PTGDR2 (0.45) | KDM4EPKMTHRATHRBPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | claimed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | claimed |