SCHEMBL8904335

SCHEMBL8904335

CCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc(C)c2C(O)=S)cc1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 4/20 0.65
AGTR1 P30556 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899458 0.94 AGTR2 (0.73) AGTR2AGTR1
SCHEMBL8900505 0.93 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL8903756 0.91 AGTR1 (0.61) AGTR2AGTR1
SCHEMBL8900417 0.85 AGTR2 (0.68) AGTR2AGTR1
SCHEMBL9135004 0.85 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL9134486 0.85 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL8903425 0.85 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL7022990 0.84 AGTR2 (0.89) AGTR2AGTR1
SCHEMBL8901703 0.84 AGTR2 (0.71) AGTR2AGTR1
SCHEMBL8898998 0.84 AGTR2 (0.69) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5604251-A Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors HOECHST AKTIENGESELLSCHAFT (DE) 1997-02-18 US disclosed