Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308518 | 0.69 | CREBBP (0.44) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL12345838 | 0.69 | CREBBP (0.44) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL6783782 | 0.69 | ANPEP (0.47) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8556056 | 0.68 | GAA (0.46) | GAAMAPTMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL2235061 | 0.68 | CREBBP (0.43) | GAAMAPTMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL2235068 | 0.68 | CREBBP (0.43) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL129351 | 0.67 | HTR2A (0.37) | GAAMEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4203755 | 0.66 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL4203753 | 0.66 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL2578087 | 0.64 | HSD17B10 (0.38) | GAAMAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |