Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904700 | 1.00 | LMNA (0.61) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL2938703 | 0.89 | LMNA (0.61) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL3437027 | 0.88 | ADORA3 (0.72) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL7198801 | 0.88 | ADORA3 (0.72) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL6560285 | 0.87 | LMNA (0.80) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL6560300 | 0.87 | LMNA (0.80) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL11311014 | 0.84 | LMNA (0.65) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL658714 | 0.84 | MEN1 (0.66) | ADORA3ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL11311023 | 0.84 | LMNA (0.65) | LMNATP53ADORA3ADORA2AADORA1 | |
| SCHEMBL20995821 | 0.84 | MEN1 (0.66) | ADORA3ADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658731-A | GENE EXPRESSION; COMPLEXING REACTIONS | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (DE) | 1997-08-19 | — | — | US | disclosed |