Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | GCLC | P48506 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | KYNU | Q16719 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814297 | 0.96 | NOS2 (0.56) | NOS2GCLCPMP22GSRKYNU | |
| SCHEMBL2244806 | 0.96 | NOS2 (0.56) | NOS2GCLCPMP22GSRKYNU | |
| Hydrochloric Acid SCHEMBL625519 | 0.94 | NOS2 (0.54) | NOS2GCLCPMP22GSRKYNU | |
| SCHEMBL27926048 | 0.81 | GCLC (0.67) | NOS2GCLCPMP22GSRPTGS1 | |
| SCHEMBL2394224 | 0.80 | NOS2 (0.55) | NOS2GCLCPMP22GSRKYNU | |
| Hydrochloric Acid SCHEMBL10649355 | 0.80 | NOS2 (0.53) | NOS2GCLCPMP22GSRKYNU | |
| SCHEMBL624998 | 0.79 | NOS2 (0.56) | NOS2GCLCPMP22GSRKYNU | |
| Taurine SCHEMBL5188521 | 0.76 | BLM (0.56) | NOS2GCLCPMP22GSRKYNU | |
| Taurine SCHEMBL5188525 | 0.76 | BLM (0.56) | NOS2GCLCPMP22GSRKYNU | |
| SCHEMBL28583479 | 0.76 | NOS2 (0.53) | NOS2GCLCPMP22GSRKYNU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238369-A1 | Conformationally Specific Viral Immunogens | CALDER BIOSCIENCES INC (US) | 2024-07-18 | — | — | US | disclosed |
| US-11993633-B2 | Conformationally stabilized RSV pre-fusion F proteins | CALDER BIOSCIENCES INC (US) | 2024-05-28 | — | — | US | disclosed |
| US-11926649-B2 | Conformationally stabilized RSV pre-fusion F proteins | CALDER BIOSCIENCES INC (US) | 2024-03-12 | — | — | US | disclosed |
| US-11752191-B2 | Conformationally-specific viral immunogens | CALDER BIOSCIENCES INC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20230054569-A1 | COMPOSITIONS AND METHODS FOR TREATING RETINITIS PIGMENTOSA | ALIA THERAPEUTICS SRL (IT) | 2023-02-23 | — | — | US | disclosed |
| US-20230053714-A1 | CONFORMATIONALLY STABILIZED RSV PRE-FUSION F PROTEINS | CALDER BIOSCIENCES INC (US) | 2023-02-23 | — | — | US | disclosed |
| US-20220288189-A1 | INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF | CALDER BIOSCIENCES INC (US) | 2022-09-15 | — | — | US | disclosed |
| US-20220119454-A1 | CONFORMATIONALLY STABILIZED RSV PRE-FUSION F PROTEINS | CALDER BIOSCIENCES INC. (US) | 2022-04-21 | — | — | US | disclosed |
| US-20210322512-A1 | CONFORMATIONALLY-SPECIFIC VIRAL IMMUNOGENS | CALDER BIOSCIENCES INC (US) | 2021-10-21 | — | — | US | disclosed |
| US-11129887-B2 | Influenza hemagglutinin proteins and methods of use thereof | CALDER BIOSCIENCES INC. (US) | 2021-09-28 | — | — | US | disclosed |
| EP-1641813-A4 | METHODS FOR OBTAINING MOLECULES WITH REDUCED IMMUNOGENICITY | AVATAR BIOTECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-7037894-B2 | Stabilized proteins | AVATAR MEDICAL, LLC (US) | 2006-05-02 | — | — | US | disclosed |
| EP-1641813-A2 | METHODS FOR OBTAINING MOLECULES WITH REDUCED IMMUNOGENICITY | Avatar Biotechnologies, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005051975-A2 | METHODS FOR OBTAINING MOLECULES WITH REDUCED IMMUNOGENICITY | AVATAR BIOTECHNOLOGIES, INC. (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050123530-A1 | Stabilized proteins | AVATAR MEDICAL, LLC (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050054572-A1 | Methods for obtaining molecules with reduced immunogenicity | CALDER BIOSCIENCES INC. | 2005-03-10 | — | — | US | disclosed |
| EP-1282722-A4 | STABILIZED PROTEINS | AVATAR MEDICAL L L C (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1282722-A1 | STABILIZED PROTEINS | Avatar Medical, L.L.C. (US) | 2003-02-12 | — | — | EP | disclosed |
| US-20020061549-A1 | Stabilized proteins | CALDER BIOSCIENCES INC. | 2002-05-23 | — | — | US | disclosed |
| WO-2001029247-A1 | STABILIZED PROTEINS | AVATAR MEDICAL, LLC (US) | 2001-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054569-A1 | COMPOSITIONS AND METHODS FOR TREATING RETINITIS PIGMENTOSA | RHOC, PDE6C, PDE6H | NOS2 3277/4885GCLC 1188/4885PMP22 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.