Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | HNF4A | P41235 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904416 | 0.94 | RXRA (0.52) | RXRARARARARBRARGRXRB | |
| SCHEMBL8904386 | 0.86 | RXRA (0.44) | RXRARARARARBRARGRXRB | |
| SCHEMBL8904383 | 0.86 | RXRA (0.44) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905703 | 0.85 | RXRA (0.43) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905707 | 0.85 | RXRA (0.43) | RXRARARARARBRARGRXRB | |
| SCHEMBL7207880 | 0.82 | RARB (0.64) | RXRARARARARBRARGRXRB | |
| SCHEMBL7207884 | 0.82 | RARB (0.64) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905104 | 0.81 | RXRA (0.49) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905864 | 0.81 | RXRA (0.49) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905251 | 0.79 | RXRA (0.53) | RXRARARARARBRARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |