Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.43 |
| ▸ | HNF4A | P41235 | 7/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905703 | 1.00 | RXRA (0.43) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8905100 | 0.85 | RXRA (0.53) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7208528 | 0.84 | RARB (0.59) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7208519 | 0.84 | RARB (0.59) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8904416 | 0.83 | RXRA (0.52) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8904383 | 0.82 | RXRA (0.44) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8904386 | 0.82 | RXRA (0.44) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8905715 | 0.81 | RXRA (0.40) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7212264 | 0.78 | RXRA (0.36) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7208553 | 0.76 | RXRA (0.55) | RXRARARARARBRARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |