Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904383 | 1.00 | RXRA (0.44) | RXRARXRBRXRGHNF4ATSHR | |
| SCHEMBL8905100 | 0.86 | RXRA (0.53) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL8904416 | 0.84 | RXRA (0.52) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL7207075 | 0.83 | RARB (0.63) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL7207067 | 0.83 | RARB (0.63) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL8905703 | 0.82 | RXRA (0.43) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL8905707 | 0.82 | RXRA (0.43) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL8904396 | 0.80 | GAA (0.42) | RXRARXRBRXRGHNF4ATSHR | |
| SCHEMBL7999260 | 0.78 | RARB (0.64) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7213602 | 0.74 | RXRA (0.55) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |