Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052307 | 0.86 | ITGB3 (0.52) | MMP2MMP9ITGB3ITGA2BNPC1 | |
| SCHEMBL8903868 | 0.85 | ITGB3 (0.49) | MMP2ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8903947 | 0.81 | F2 (0.49) | ITGB3ITGA2BNPC1RAB9AMEN1 | |
| SCHEMBL8903290 | 0.80 | HDAC8 (0.47) | MMP2ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8904345 | 0.76 | NPC1 (0.43) | NPC1RAB9AMEN1MAPTTSHR | |
| SCHEMBL8712906 | 0.75 | TP53 (0.46) | ITGB3ITGA2BMAPTTSHRHSD17B10 | |
| SCHEMBL8906181 | 0.73 | ENPP2 (0.38) | NPC1RAB9AMEN1MAPTTSHR | |
| SCHEMBL8904266 | 0.71 | NPC1 (0.44) | ITGB3ITGA2BNPC1RAB9AMEN1 | |
| SCHEMBL8903880 | 0.70 | F2 (0.41) | MMP9ITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL8903850 | 0.70 | ITGB3 (0.68) | MMP2ITGB3ITGA2BITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |