Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904266 | 0.89 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL8712906 | 0.79 | TP53 (0.46) | SMN1; SMN2TP53MAPTTSHRHSD17B10 | |
| SCHEMBL8905173 | 0.76 | MMP2 (0.42) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL9052307 | 0.74 | ITGB3 (0.52) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL8903290 | 0.73 | HDAC8 (0.47) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL8903947 | 0.73 | F2 (0.49) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL8718835 | 0.72 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL8719741 | 0.71 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL7627031 | 0.71 | ALDH1A1 (0.49) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8713275 | 0.71 | ITGB3 (0.51) | NPC1RAB9ASMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |