Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.43 |
| ▸ | KLK1 | P06870 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 8/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317894 | 0.90 | MMP2 (0.48) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL6319054 | 0.90 | MMP2 (0.48) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL8904944 | 0.82 | MMP2 (0.46) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL6318207 | 0.81 | KLKB1 (0.39) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL6320132 | 0.80 | GHSR (0.46) | KLKB1KLK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6320121 | 0.80 | GHSR (0.46) | KLKB1KLK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6319663 | 0.80 | KLKB1 (0.40) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL6319699 | 0.80 | KLKB1 (0.43) | MMP9MMP2MMP8KLKB1KLK1 | |
| SCHEMBL8905784 | 0.80 | MMP1 (0.48) | MMP9MMP2MMP8CTSLCTSS | |
| SCHEMBL6319176 | 0.79 | KLKB1 (0.37) | MMP9MMP2MMP8KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |