SCHEMBL8905382

SCHEMBL8905382

CC(C)C([Al])(Oc1c(C(C)(C)C)cccc1C(C)(C)C)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 1/20 0.33
KIF11 P52732 1/20 0.33
ATM Q13315 1/20 0.33
NR1H4 Q96RI1 1/20 0.31
NLRP3 Q96P20 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8599850 0.79 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL12488403 0.74 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL20268797 0.71 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL2855725 0.70 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TDP1
Isopropyl Alcohol SCHEMBL22712567 0.69 CA2 (0.43) CA2GABRA1GABRB2ALDH1A1TDP1
Hydrochloric Acid SCHEMBL28478139 0.69 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL6823125 0.69 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TDP1
Hydrochloric Acid SCHEMBL727524 0.69 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL3096012 0.68 CA2 (0.50) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL26875764 0.67 GABRA1 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656704-A POLYMETHYL METHACRYLATE; HIGH STRENGTH, HEAT RESISTANT, RADIATION TRANSPARENT ELF ATOCHEM S.A. (FR) 1997-08-12 US claimed