SCHEMBL12488403

SCHEMBL12488403

CC(C)(C)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.48
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KIF11 P52732 1/20 0.35
ALOX12 P18054 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NR1H4 Q96RI1 1/20 0.32
NLRP3 Q96P20 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12355664 0.89 CA2 (0.43) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL11954818 0.87 GABRA1 (0.50) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL6783300 0.85 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL20268797 0.81 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL8599850 0.81 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL180679 0.80 CA2 (0.43) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL11884979 0.80 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28214308 0.80 ALOX12 (0.38) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL332092 0.79 ALDH1A1 (0.44) CA2ALDH1A1TDP1KDM4ENR1H4
SCHEMBL1405888 0.78 ALDH1A1 (0.42) CA2ALDH1A1TDP1KDM4ENR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2683749-B1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS GRACE W R & CO (US) 2023-06-07 EP claimed
CN-103534278-B Aluminoxane catalyst activators containing carbocationic agents and their use in polyolefin catalysts 阿尔比马尔公司 2016-10-05 CN claimed
US-9090720-B2 Aluminoxane catalyst activators containing carbocation agents, and use thereof in polyolefin catalysts ALBEMARLE CORPORATION (US) 2015-07-28 US claimed
CN-103534278-A Aluminoxane catalyst activators containing carbocationic agents and their use in polyolefin catalysts ALBEMARLE CORP 2014-01-22 CN claimed
EP-2683749-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS Albemarle Corporation (US) 2014-01-15 EP claimed
US-20130345376-A1 Aluminoxane Catalyst Activators Containing Carbocation Agents, and use thereof in Polyolefin Catalysts ALBEMARLE CORPORATION (US) 2013-12-26 US claimed
WO-2012122332-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS ALBEMARLE CORPORATION (US) 2012-09-13 WO claimed
US-20240228682-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2024-07-11 US disclosed
CN-118005533-A Preparation method of chiral cyano amine derivative 西湖大学 2024-05-10 CN disclosed
EP-4337703-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W. R. Grace & Co.-Conn (US) 2024-03-20 EP disclosed
CN-117616055-A Polyethylene copolymers with broad short chain branching distribution 格雷斯公司 2024-02-27 CN disclosed
EP-2683749-B1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS GRACE W R & CO (US) 2023-06-07 EP disclosed
WO-2022241225-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2022-11-17 WO disclosed
US-20200247826-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2020-08-06 US disclosed
CN-103534278-B Aluminoxane catalyst activators containing carbocationic agents and their use in polyolefin catalysts 阿尔比马尔公司 2016-10-05 CN disclosed
US-9090720-B2 Aluminoxane catalyst activators containing carbocation agents, and use thereof in polyolefin catalysts ALBEMARLE CORPORATION (US) 2015-07-28 US disclosed
EP-2683749-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS Albemarle Corporation (US) 2014-01-15 EP disclosed
US-20130345376-A1 Aluminoxane Catalyst Activators Containing Carbocation Agents, and use thereof in Polyolefin Catalysts ALBEMARLE CORPORATION (US) 2013-12-26 US disclosed
WO-2012122332-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS ALBEMARLE CORPORATION (US) 2012-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200247826-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE UROD, ALDH1A2, UBE2I CA2 4695/4885GABRA1 1918/4885GABRB2 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.