SCHEMBL8905568

SCHEMBL8905568

CCCCS(=O)(=O)N[C@@H](Cc1ccc(NC(=O)c2cc3cc(C(=N)N)ccc3o2)cc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 15/20 0.68
ITGA2B P08514 15/20 0.68
F2 P00734 1/20 0.45
PLG P00747 1/20 0.45
PLAU P00749 1/20 0.45
PLAT P00750 1/20 0.45
KLKB1 P03952 1/20 0.45
PRSS1 P07477 1/20 0.45
MMP2 P08253 3/20 0.43
ITGB1 P05556 1/20 0.42
ITGAV P06756 1/20 0.42
ITGB5 P18084 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903850 1.00 ITGB3 (0.68) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8713085 0.92 ITGB3 (0.60) ITGB3ITGA2BF2PLGPLAU
SCHEMBL9052307 0.86 ITGB3 (0.52) ITGB3ITGA2BMMP2ITGAV
SCHEMBL8903869 0.85 ITGB3 (0.54) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8905600 0.85 ITGB3 (0.54) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8903868 0.84 ITGB3 (0.49) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8716564 0.82 ITGB3 (0.56) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8770351 0.81 ITGB3 (0.61) ITGB3ITGA2BPLAUITGB1ITGAV
SCHEMBL8712842 0.80 ITGB3 (0.53) ITGB3ITGA2BF2PLGPLAU
SCHEMBL8904811 0.79 ITGB3 (0.60) ITGB3ITGA2BF2PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635527-A ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES THE GREEN CROSS CORPORATION (JP) 1997-06-03 US disclosed
EP-0712844-A1 NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF THE GREEN CROSS CORPORATION (JP) 1996-05-22 EP disclosed