Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.60 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905568 | 0.92 | ITGB3 (0.68) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8903850 | 0.92 | ITGB3 (0.68) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8712774 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BMAPTMEN1NPC1 | |
| SCHEMBL8904310 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8716564 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL9052307 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BMAPTMEN1NPC1 | |
| SCHEMBL8712842 | 0.77 | ITGB3 (0.53) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8903869 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8905600 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BPLGPLAUPLAT | |
| SCHEMBL8903868 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BPLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |