SCHEMBL8716564

SCHEMBL8716564

CCCCS(=O)(=O)NC(C)C(=O)Oc1ccc(NC(=O)c2cc3cc(C(=N)N)ccc3o2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 7/20 0.56
ITGA2B P08514 7/20 0.56
PLG P00747 3/20 0.43
PLAU P00749 3/20 0.43
PLAT P00750 3/20 0.43
KLKB1 P03952 3/20 0.43
PRSS1 P07477 3/20 0.43
F2 P00734 2/20 0.43
MAPT P10636 5/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP3 P42574 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718070 0.84 SMN1; SMN2 (0.44) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8713085 0.84 ITGB3 (0.60) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8905568 0.82 ITGB3 (0.68) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8903850 0.82 ITGB3 (0.68) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8718226 0.82 SMN1; SMN2 (0.52) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8718457 0.79 PLG (0.55) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8719741 0.78 SMN1; SMN2 (0.47) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8712842 0.77 ITGB3 (0.53) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8713127 0.77 MAPT (0.47) ITGB3ITGA2BPLGPLAUPLAT
SCHEMBL8718100 0.74 TPSAB1 (0.66) ITGB3ITGA2BPLGPLAUPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753670-A ANTICOAGULANTS THE GREEN CROSS CORPORATION (JP) 1998-05-19 US disclosed