SCHEMBL8905576

SCHEMBL8905576

[CH2]Cc1cc(C(=O)O)cc2c1C(=O)NC2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TPMT P51580 1/20 0.41
▸ TDP2 O95551 3/20 0.39
▸ HCAR1 Q9BXC0 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ POLB P06746 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ RECQL P46063 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ PKM P14618 1/20 0.34
▸ APEX1 P27695 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ GSK3B P49841 2/20 0.34
▸ CDK4 P11802 1/20 0.34
▸ CCND1 P24385 1/20 0.34
▸ MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4597241 0.83 TPMT (0.40) TPMTTDP2HCAR1ALDH1A1MEN1
SCHEMBL10356494 0.78 TPMT (0.40) TPMTTDP2HCAR1ALDH1A1MEN1
SCHEMBL9636429 0.77 PLA2G2A (0.41) ALDH1A1MEN1MAPTKMT2A
SCHEMBL5029815 0.76 MAPT (0.53) TPMTTDP2HCAR1ALDH1A1MEN1
SCHEMBL8756369 0.72 TDP2 (0.50) TPMTTDP2TTRTSHR
SCHEMBL5142096 0.70 TPMT (0.37) TPMTTDP2HCAR1ALDH1A1MEN1
SCHEMBL7589413 0.69 TTR (0.49) TPMTTDP2HCAR1ALDH1A1MEN1
SCHEMBL5167684 0.67 GSK3B (0.46) ALDH1A1MEN1POLBCYP3A4MAPT
SCHEMBL8757366 0.67 WEE1 (0.50) TDP2MEN1KMT2ATDP1CDK4
SCHEMBL29703129 0.66 TDP2 (0.59) TDP2MEN1POLBKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4012555-A Self-bonding varnish for magnet wires comprising a combination of a polyalkylenetrimellitate imide and a polyalkylenetrimellitate ester imide STANDARD OIL COMPANY (INDIANA) (US) 1977-03-15 — — US claimed
US-3944706-A MAGNET WIRE STANDARD OIL COMPANY (US) 1976-03-16 — — US claimed
EP-0764678-A2 A thermoplastic resin film and a method for producing the same Toyo Boseki Kabushiki Kaisha (JP) 1997-03-26 — — EP disclosed
US-5574119-A BIAXIALLY-ORIENTED, MINIMIZED BOWING, HEAT SHRINKAGE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1996-11-12 — — US disclosed
US-5411695-A Thermoplastic resin film and a method for producing the same TOYO BOSEKI KABUSHIKI KAISHA (JP) 1995-05-02 — — US disclosed
EP-0423630-A2 A thermoplastic resin film and a method for producing the same Toyo Boseki Kabushiki Kaisha (JP) 1991-04-24 — — EP disclosed
US-4245086-A BY REACTING TRIMELLITIC ACID ANHYDRIDE WITH A MONOALKANOLAMINE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1981-01-13 — — US disclosed
US-4130551-A Solid state polymerization STANDARD OIL COMPANY (INDIANA) (US) 1978-12-19 — — US disclosed
US-4124419-A POLYALKYLENETRIMETLLITATE IMIDE POLYALKYLENETRIMELLITATE ESTER IMIDES STANDARD OIL COMPANY (US) 1978-11-07 — — US disclosed
US-4070524-A Self-bonding varnish for magnetic wire comprising polyalkylenetrimellitate imide polyalkylenetrimellitate ester STANDARD OIL COMPANY (INDIANA) (US) 1978-01-24 — — US disclosed
US-4012555-A Self-bonding varnish for magnet wires comprising a combination of a polyalkylenetrimellitate imide and a polyalkylenetrimellitate ester imide STANDARD OIL COMPANY (INDIANA) (US) 1977-03-15 — — US disclosed
US-4012556-A Self-bonding varnish for magnet wires comprising a polyalkylenetrimellitate ester imide STANDARD OIL COMPANY (INDIANA) (US) 1977-03-15 — — US disclosed
US-4008206-A Solid state polymerization STANDARD OIL COMPANY (INDIANA) (US) 1977-02-15 — — US disclosed
US-3944706-A MAGNET WIRE STANDARD OIL COMPANY (US) 1976-03-16 — — US disclosed
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