Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 3/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636429 | 0.85 | PLA2G2A (0.41) | HCAR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4597241 | 0.82 | TPMT (0.40) | TPMTHCAR1TDP2CHEK1TTR | |
| SCHEMBL8905576 | 0.78 | TPMT (0.41) | TPMTHCAR1TDP2CHEK1TTR | |
| SCHEMBL8969034 | 0.72 | PARP1 (0.42) | CASP3CHEK1CASP2CASP7CASP6 | |
| SCHEMBL5029815 | 0.71 | MAPT (0.53) | TPMTHCAR1TDP2TTRCASP7 | |
| SCHEMBL3747455 | 0.68 | F13A1 (0.38) | TTRF13A1CASP7MEN1ALDH1A1 | |
| SCHEMBL8503573 | 0.68 | F13A1 (0.38) | TTRF13A1CASP7MEN1ALDH1A1 | |
| SCHEMBL7896830 | 0.68 | F13A1 (0.38) | TTRF13A1CASP7MEN1ALDH1A1 | |
| Butyl Chloride SCHEMBL10492137 | 0.68 | MEN1 (0.51) | TDP2CASP3CHEK1TTRMEN1 | |
| SCHEMBL5312970 | 0.67 | GSK3B (0.41) | CASP3CHEK1CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182745-B1 | POLYIMIDES, PROCESS FOR THEIR FABRICATION, AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | disclosed |